Trypanosoma brucei brucei VSG-seq. Trypanosoma brucei brucei
收藏NIAID Data Ecosystem2026-03-09 收录
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资源简介：
Sequencing data from experiments examining VSG repertoire during T. brucei mouse infections, using VSG-seq.
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创建时间：
2014-12-17
相关数据集
Loss of an ectopic VSG is dependent on active transcription and does not disrupt the number or variety of templates used to repair a BES DSB. Transcription dependent loss of an ectopic VSG
In the mammalian host, Trypanosoma brucei is coated in a single variant surface glycoprotein (VSG) species. Stochastic switching of the expressed VSG allows the parasite to escape detection by the hos
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Transcriptome sequencing of bloodstream form Trypanosoma brucei expressing VSG121. Transcriptome sequencing of bloodstream form Trypanosoma brucei expressing VSG121
Cells were grown in HMI-9 and RNA prepared using QIAGEN RNAeasy kit.
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Up regulated Variant Surface Glycoproteins under TDP1 overexpression
Trypanosoma brucei parasites successfully evade the host immune system by periodically switching the dense coat of Variant Surface Glycoproteins (VSG) at the cell surface. Each parasite expresses VSGs
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TbRAP1's dsDNA binding activity plays an important role in subtelomeric gene expression regulation. TbRAP1's dsDNA binding activity plays an important role in subtelomeric gene expression regulation
We examine the function of the TbRAP1 DB domain in gene expression regulation in Trypanosoma brucei that causes human African trypanosomiasis. TbRAP1 is required for normal VSG monoallelic expression,
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