Cryo-EM structure of MraY in complex with analogue 2

Cryo-EM structure of MraY in complex with analogue 2 Descriptor: (2~{S},3~{S})-3-[(2~{S},3~{R},4~{S},5~{R})-5-(aminomethyl)-3,4-bis(oxidanyl)oxolan-2-yl]oxy-2-[[3-[[[(2~{S})-6-azanyl-2-(hexadecanoylamino)hexanoyl]amino]methyl]phenyl]methylamino]-3-[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]propanoic acid, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase Authors: Hao, A, Lee, S.-Y. Deposit date: 2024-03-26 Release date: 2024-06-26 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target. Nat Commun, 15, 2024