Excel file containing individual animal-level data required to reproduce the results. The SFI dataset includes measurements at 4, 8, 12, and 16 weeks, whereas all other outcomes were collected at the
an = 1 for each virus group. bThe maximum percent weight loss during the 21 days p.i. Numbers in parentheses indicate the day of maximum weight loss. cUpper respiratory tract inflammation was defined
RML prions were propagated in vitro by sPMCA with purified CHO-expressed PrPC+Prnp0/0 brain homogenate. aGenerated by in vitro propagation of ΔC-PBD PrPSc (Figure 2). bPropagation in mock-purified unt
We performed real-time, quaking-induced conversion with NaPTA pre-treatment on homogenates of the same tissues in CWD-inoculated white-tailed deer. We included 5 deer that were euthanized in symptomat