Ferritin-based MRI of dendritic cell

Figure 1. Analysis of dendritic cell (DC) transduced with myc-tagged human ferritin heavy chain (FTH) and green fluorescence prtein (GFP) using lentivirus. Figure 2. Analyses of proliferation and migration activities and co-stimulatory molecules expressions in dendritic cell (DC) and human ferritin heavy chain-transduced DC (FTH-DC). Figure. 3. Cellular iron staining, iron amount measurement and in vitro MRI analysis of dendritic cell (DC) and human ferritin heavy chain-transduced DC (FTH-DC). Figure 4. in vivo and ex vivo MRI of popliteal lymph nodes (LNs) of mouse injected with dendritic cell (DC) and ferritin heavy chain-transduced DC (FTH-DC). Figure 5. Histological analysis of cryosectioned popliteal lymph nodes (LNs) with dendritic cell (DC) and ferritin heavy chain-transduced DC (FTH-DC).图1. 慢病毒转染 myc标签标记的人铁蛋白重链（human ferritin heavy chain, FTH）与绿色荧光蛋白（green fluorescence protein, GFP）的树突状细胞（dendritic cell, DC）分析。图2. 树突状细胞（DC）与转染人铁蛋白重链的树突状细胞（FTH-DC）的增殖、迁移活性及共刺激分子表达分析。图3. 树突状细胞（DC）与转染人铁蛋白重链的树突状细胞（FTH-DC）的细胞铁染色、铁含量测定及体外磁共振成像（MRI）分析。图4. 注射树突状细胞（DC）与转染铁蛋白重链的树突状细胞（FTH-DC）的小鼠腘窝淋巴结（popliteal lymph nodes, LNs）的体内与离体磁共振成像（MRI）。图5. 注射树突状细胞（DC）与转染铁蛋白重链的树突状细胞（FTH-DC）的小鼠腘窝淋巴结（LNs）冰冻切片的组织学分析。