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Transcriptome analysis ofAAV production

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NIAID Data Ecosystem2026-03-11 收录
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In this study, a novel adeno-associated virus (AAV) production protocol utilizing small regulatory RNAs (miRNA) in order to increase its potency was developed. We further assessed the modulation of cellular transcriptome during AAV vector packaging of this new production strategy. This was crucial to delineate the alterations to host cell gene expression during AAV packaging.

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2019-09-07
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