Malignant carcinomas that recur following therapy are typically de-differentiated and multidrug resistant (MDR). De-differentiated cancer cells acquire MDR by up-regulating reactive oxygen species (RO
P-Glycoprotein, a member of the ATP-binding cassette (ABC) superfamily, is a multidrug transporter responsible for cellular efflux of hundreds of structurally unrelated compounds, including natural pr
Twelve undescribed jatrophane diterpenoids, euphpepluones A–L (1–12), together with seven known analogues (13–19), were isolated from the whole plant of Euphorbia peplus, and their structures were elu
Crystal structure of the Ethidium bound RamR determined with XtaLAB Synergy Descriptor: ETHIDIUM, Putative regulatory protein, SULFATE ION Authors: Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. D
