Perceived water-related risk factors of Buruli ulcer in two villages of south-central Côte d'Ivoire
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2024-07-15
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Photodegradation of the Mycobacterium ulcerans Toxin, Mycolactones: Considerations for Handling and Storage
BackgroundMycolactones are toxins secreted by M. ulcerans, the etiological agent of Buruli ulcer. These toxins, which are the main virulence factors of the bacilli, are responsible for skin lesions. C
NIAID Data Ecosystem70
Clinical samples and laboratory results of primary and secondary BUD lesions.
Table 1 shows samples collected from the primary and secondary lesions in July 2010 and 2011 and the corresponding laboratory results. “Neg” indicates a negative test result, “pos” indicates a positiv
Figshare2015-12-02 更新40
Summary of activities and behaviours that influence odds of developing Buruli ulcer infection.
Data were taken from case–control studies conducted in regions of Africa endemic for Buruli ulcer. OR refers to the odds of developing Buruli ulcer in cases compared to noninfected controls for “risk
Figshare2021-08-26 更新20
Population age distribution and age adjusted cumulative BU incidence rate in the Bankim HD.
In the course of the exhaustive survey, data on the population age structure of the Bankim HD were collected (A). Using this age distribution and the ages of the RT-PCR confirmed BU cases which occurr
Figshare2016-02-24 更新60
We showed that M. ulcerans-specific DNA sequences were detected on the unbreached skin of 6/52 (11.5%) asymptomatic farmers living in Sindou versus 0/52 (0%) of those living in the non-endemic region of Tenkodogo. Then, we cultured the skin microbiota of asymptomatic M. ulcerans carriers and negative control individuals, all living in the region of Sindou. A total of 84 different bacterial and fungal species were isolated, 21 from M. ulcerans-negative skin samples, 31 from M. ulcerans-positive samples and 32 from both. More specifically, Actinobacteria, Aspergillus niger and Aspergillus flavus were significantly associated with M. ulcerans skin carriage.. Investigation of skin microbiota reveals Mycobacterium ulcerans-Aspergillus sp. trans-kingdom communication.
Mycobacterium ulcerans secrete a series of non-ribosomal-encoded toxins known as mycolactones that are responsible for causing a disabling ulceration of the skin and subcutaneous tissues named Buruli
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