DCE-MRI prostate images
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A 3mm slice fat-suppressed T2W fast spin-echo sequence (TR/TE/ETL: 3400 ms/85 ms/13) is used to acquire images in sagittal and oblique coronal planes, the latter planes being orientated perpendicular or parallel to the prostate PZ – rectal wall axis. Three-dimensional T2W fast spin-echo (TR/TE/ETL: 3600 ms}/143 ms/109, slice thickness: 1.25 mm) images are then acquired in an oblique axial plane.The nominal matrix and FoV of the 3D T2W fast spin-echo images are 320x256 and 280x240 mm2, respectively, thereby affording sub-millimetric pixel resolution within the imaging plane. DCE-MRI is performed using a fat suppressed 3D T$_1$ VIBE sequence (TR/TE/Flip angle: 3.25 ms/1.12 ms/10 degrees; Matrix: 256x192; FoV: 280x210 (with 75% rectangular FoV); slab of 16 partitions of 3.5 mm thickness; temporal resolution: 6 s/slab over approximately 5 min). A power injector (Medrad, Indianola, USA) is used to provide a bolus injection of Gd-DTPA (Dotarem, Guerbet, Roissy, France) at a dose of 0.2 ml Gd-DTPA/kg of body weight.
本数据集的影像采集采用如下方案:首先采用3mm层厚脂肪抑制T2加权快速自旋回波序列(TR/TE/ETL:3400ms/85ms/13)采集矢状位及斜冠状位图像,其中斜冠状位平面垂直或平行于前列腺外周带(Peripheral Zone, PZ)-直肠壁轴线。随后以斜轴位采集三维T2加权快速自旋回波图像,其参数为TR/TE/ETL:3600ms/143ms/109,层厚1.25mm。该三维T2加权快速自旋回波序列的标称矩阵与视野(Field of View, FoV)分别为320×256与280×240 mm²,由此可在成像平面内实现亚毫米级像素分辨率。动态对比增强磁共振成像(Dynamic Contrast-Enhanced MRI, DCE-MRI)采用脂肪抑制三维T1加权容积内插屏气检查(Volume Interpolated Breath-hold Examination, VIBE)序列采集,具体参数如下:TR/TE/翻转角:3.25ms/1.12ms/10°;矩阵:256×192;视野:280×210(采用75%矩形视野);扫描层块包含16个分区,每个分区层厚3.5mm;时间分辨率为6秒/层块,总采集时长约5分钟。本次扫描使用高压注射器(Medrad,美国印第安诺拉),以0.2ml Gd-DTPA/公斤体重的剂量团注钆喷酸葡胺(Gd-DTPA,商品名Dotarem,盖尔伯特公司,法国鲁瓦西)。




