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Additive and multiplicative interactions of maternal mild thyroid dysfunction and preschoolers’ neurodevelopment
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2022-10-10
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Associations between cognitive outcomes and head circumference growth trajectories. This table presents the results of linear regression analyses assessing the associations between cognitive outcomes and head circumference growth, as determined by latent class trajectory modelling and linear mixed modelling. The latent class trajectory model estimates compare the “Increasing” (26%) class to the “Reference” (74%) class. Estimates for linear mixed model slope and intercept are interpreted as the effect of 1 standard deviation within our population. The table provides both unadjusted and adjusted associations, with the latter controlling for potential confounders such as pre-pregnancy maternal body mass index, child sex, birth weight, gestational age, smoking during pregnancy, antibiotic use during pregnancy, pre-eclampsia, household income at birth, maternal education level at birth and maternal age at birth. Further adjustments include maternal and child poly
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