Bulk and single-cell RNA-seq performed on primary AML blasts cultured ex vivo for 3 days in standard or niche-like conditions.EGA study EGAS00001006265
We used scRNA seq on regenerating PDX models and de novo AML patient cells to delineate the heirarchical regeneration of AML following treatment Overall design: Bone Marrow from AML PDXs were isolated
Single-cell RNA sequencing was performed on bone marrow mononuclear cells of a patient with acute myeloid leukemia with erythroid differentiation of the blasts and on peripheral blood mononuclear cell
Transcription profiling of human primary CD34+ acute myelogenous leukemia specimens obtained from 12 patients treated with 7.5 micromolar parthenolide (PTL)