THpdb

THPdb is a comprehensive database based on approved and approved/investigational therapeutic peptides compiling important information about these peptides, like their description, sequence, indication, mechanism of action, pharmacodynamics, toxicity, metabolism, absorption, half life, volume of distribution, clearance rate, patent information, interaction with other drugs, targets, physicochemical properties, etc. These peptides have been classified into four categories according to their application, making it easy for the user to access them. Therapeutic peptides are modified in different ways so as to alter their properties and then sold under different brand names by various companies. THPdb provides detailed description of such brands in a user-friendly way to enable quick access of relevant information on the peptides. All information compiled in this database has been extracted from research papers, patents, pharmaceutical company websites catering to product details, drugbank, US-FDA and others.

THPdb是一款基于已获批及获批/研发中治疗性肽（therapeutic peptides）构建的综合性数据库，收录了此类肽类的多项关键信息，包括其概述、序列、适应症、作用机制、药效学、毒性、代谢、吸收、半衰期、分布容积、清除率、专利信息、药物相互作用、作用靶点以及理化性质等。此类肽类已根据应用场景划分为四大类别，便于用户检索获取。治疗性肽类可通过多种修饰手段改变其特性，随后由多家企业以不同商品名推向市场。THPdb以友好易用的方式详细记载了此类商品名的相关信息，助力用户快速获取目标肽类的关联资料。本数据库收录的所有信息均源自学术论文、专利、药企官方产品详情网站、DrugBank、美国食品药品监督管理局（US-FDA）等权威公开渠道。

搜集汇总

背景与挑战

背景概述

THpdb是一个综合性的治疗性肽类数据库，专注于编译已批准或研究中的肽类详细信息，包括序列、适应症、作用机制、药效学、毒性、代谢、专利等关键数据。肽类根据应用分为四类，便于用户快速访问，并详细描述了经过修饰后以不同品牌名称销售的情况。所有信息来源于研究论文、专利、制药公司网站、DrugBank和美国FDA等权威来源，旨在为用户提供全面、易于访问的肽类治疗信息。