Osteogenesis Imperfecta (OI) is a genetic, rare disease characterized by bone fragility, with a wide range in the severity of clinical manifestations. The majority of the cases are due to mutations in
BACKGROUND: Pancreatic islet transplantation is the most potential method for radical treatment of type 1 diabetes. The early hypoxia death after transplantation impedes the success of its treatment.
Myeloid cells have been identified as hematopoietic stem cell (HSC)-regulating cells. However, the mechanisms by which myeloid cells regulate the function of HSCs are not fully defined. Our previous s