NonmetricANOVA

Nonmetric Analysis of Variance manuscript_code.Rmd file provides codes that are needed to reproduce analyses and figures for the manuscript. nm_ANOVA.R file contains the nmANOVA algorithm as a function of dissimilarity measures and partitions selected for testing. SD1.xlsx is a file with supplementary information. It contains BLAST bit scores for 78 angiosperms (Section: Phylogenetic bipartition assessment with BLAST bit scores). SD2.xslx is a file with supplementary information. It contains combination sensitivity scores from O'Neil study (O'Neil et.al. 2016) obtained from DrugComb portal (Section: Drug combination sensitivity scoring for cell lines). SD3.RData is a file with supplementary information. It provides Kullback-Leibler scores for the bladder cancer dataset used in the study (Section: Kullback-Leibler divergence for gene expression data).非度量方差分析（Nonmetric Analysis of Variance）配套的manuscript_code.Rmd文件提供了复现该手稿中所有分析与图表所需的代码。nm_ANOVA.R文件包含了nmANOVA算法，该算法是一个以相异度测度（dissimilarity measures）与待测试的划分（partitions selected for testing）为参数的函数。SD1.xlsx为补充信息文件，内含78种被子植物（angiosperms）的BLAST比特分值（BLAST bit scores），对应章节为「基于BLAST比特分值的系统发育二分划分评估」。SD2.xlsx为补充信息文件，内含来自O'Neil等（O'Neil et.al. 2016）研究的联合用药敏感性评分，该数据集从DrugComb门户（DrugComb portal）获取，对应章节为「细胞系的联合用药敏感性评分」。SD3.RData为补充信息文件，提供了本研究使用的膀胱癌数据集的库尔贝克-莱布勒分值（Kullback-Leibler scores），对应章节为「基因表达数据的库尔贝克-莱布勒散度」。

搜集汇总

背景与挑战

背景概述

该数据集提供了非度量方差分析（nmANOVA）的算法实现和复现代码，并包含多个生物学领域的补充数据，如系统发育评估、药物敏感性评分和基因表达差异分析，适用于研究组间差异的统计检验。