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The Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation

ChEBI2012-10-01 更新2026-07-21 收录

细胞分化调控

转录机制研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40286 数据链接链接失效反馈

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The Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation

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创建时间：

2012-10-01

棕色脂肪组织

细胞分化调控

Brown adipose tissue (BAT) plays critical thermogenic, metabolic and endocrine roles in mammals, and aberrant BAT function is associated with metabolic disorders including obesity and diabetes. The ma

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Investigation of molecular events underlying the IL-6-mediated Th1 inhibition in tumor-bearing mice. Mus musculus

肿瘤免疫微环境

细胞分化调控

To understand the molecular mechanism underlying the IL-6-mediated attenuation of Th1 differentiation in tumor-bearing animals, we have employed whole genome microarray expression profiling of CD4+ T

NIAID Data Ecosystem40

Integrative analysis of single-cell ATAC-seq and RNA-seq using Self-Organizing Maps [scRNA-Seq]

单细胞多组学

细胞分化调控

We have developed a computational approach that uses self-organizing maps for integrative genomic analysis. We utilize this approach to identify the single-cell chromatin and transcriptomic profiles d

NIAID Data Ecosystem30

Table1_Monocytic Myeloid-Derived Suppressor Cells Inhibit Myofibroblastic Differentiation in Mesenchymal Stem Cells Through IL-15 Secretion.docx

纤维化机制

细胞分化调控

Background: Accumulating evidence indicates that mesenchymal stem cells (MSCs) are precursors of myofibroblasts, which play a vital role in renal fibrosis. The close interaction between MSCs and other

NIAID Data Ecosystem40

Table_2_T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.xlsx

细胞分化调控

过继性细胞疗法

T-bet and Eomes are transcription factors that are known to be important in maturation and function of murine natural killer (NK) cells. Reduced T-BET and EOMES expression results in dysfunctional NK

NIAID Data Ecosystem30

The Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation

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