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Mode of action studies with DNDi6174 in Leishmania donovani. Mode of action studies with DNDi6174 in Leishmania donovani

NIAID Data Ecosystem2026-03-12 收录

抗利什曼原虫药物机制

药物靶点研究

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJEB45584 数据链接链接失效反馈

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资源简介：

Mode of action studies with DNDi6174 in Leishmania donovani

应用场景：

创建时间：

2021-08-10

结构生物学

药物靶点研究

human dihydrofolate reductase complex with NADPH and 5-methyl-6-(phenylthio-4'trifluoromethyl)thieno[2,3-d]pyrimidine-2,4-diamine Descriptor: 5-methyl-6-{[4-(trifluoromethyl)phenyl]sulfanyl}thieno[2,3

Protein Data Bank Japan2023-09-27 更新50

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN

蛋白质结构解析

药物靶点研究

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN Descriptor: CALCIUM ION, SULFATE ION, TRYPSIN, ... Authors: Stubbs, M.T. Deposit date: 1999-08-24 Release date: 2000-08-25 Last modified: 20

Protein Data Bank Japan2024-11-13 更新40

Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-BUTYL-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, IPP and Ca2+

结构生物学

药物靶点研究

Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-BUTYL-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, IPP and Ca2+ Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 3

Protein Data Bank Japan2024-11-27 更新20

REV-ERBα Ameliorates Heart Failure Through Transcription Repression

心力衰竭分子机制

药物靶点研究

Heart failure remains a major unmet clinical need and current therapies targeting neurohomonal and hemodynamic regulation have limited efficacy. We report that pharmacological activation of the trans

NIAID Data Ecosystem50

LDHU3_18.1400

寄生虫生物化学

药物靶点研究

cAMP phosphodiesterase A | PDEA; Leishmania donovani (HU3 strain)

Mendeley Data30