The spindle checkpoint prevents activation of the anaphase-promoting complex (APC/C) until all chromosomes are correctly attached to the mitotic spindle. Early in mitosis, the mitotic checkpoint compl
The conserved Mps1 kinase corrects improper kinetochore-microtubule attachments, thereby ensuring chromosome biorientation. Yet, its critical targets in this process remain elusive. Mps1 is also invol
The first sheet contains the molecules of (active) Tem1-GTP at the SPB in simulations of wild-type, Bfa1-SPB, and bfa1Δ cells as calculated from the ODE model of Caydasi and colleagues (2012). Spindle
