U87-CBG-GFP cells selected with blasticidin to stably express Cas9 were transduced with an MOI (< 1) of Brunello guide library (with puromycin resistance in the guide backbone). Cells were rested for
Genome wide CRISPR screen was performed to find resistance to targeted drugs for melanoma and lung . This dataset contains all the data available for this study on 2019-08-28.EGA dataset EGAD00001005
Single Cell Databases of Cell Painting Profiles for the Cell Health Project. These data are used to aggregate profiles in a CRISPR knockout experiment. The data are used to predict cell health assays.
Genome-wide CRISPR/Cas9-based screen to identify positive regulators of p53 function Overall design: CHP212 cells transduced with the GeCKOv2 A and B libraries were treated with 2 rounds of Nutlin to