During vertebrate evolution, complex organs have evolved several times. It has been hypothesized that gene duplications can drive the evolution of new complex traits. However, testing this prediction
Metazoans respond to hypoxic stress via the Hypoxia Inducible Factor (HIF) pathway, a mechanism thought to be extremely conserved due to its importance in monitoring cellular oxygen levels and regulat
Stem cell-derived islet (SC-islet) cell therapy holds immense potential for the treatment of Type 1 Diabetes. However, low oxygen supply leads to cell dysfunction post-transplantation, especially in s
Breath-holding foraging implies adaptations to limit oxygen depletion and maximize foraging time. Physiological adjustments can be mediated through oxygen consumption and muscle mitochondria, which al
