A Structure-Based Library Approach to Kinase Inhibitors

NIAID Data Ecosystem2026-03-06 收录

激酶抑制剂

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数据链接：

https://figshare.com/articles/dataset/A_Structure-Based_Library_Approach_to_Kinase_Inhibitors/3661437 数据链接链接失效反馈

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资源简介：

A Structure-Based Library Approach to Kinase Inhibitors

创建时间：

2016-08-18

Crystal structure of BCL6 BTB domain with compound 15f

结构生物学

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Crystal structure of BCL6 BTB domain with compound 15f Descriptor: B-cell lymphoma 6 protein, N-[2-(1H-indol-3-yl)ethyl]-N'-{3-[(4-methylpiperazin-1-yl)methyl]-1-[2-(morpholin-4-yl)-2-oxoethyl]-1H-ind

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Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity

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分子相互作用

Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity Descriptor: (2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMIN

Protein Data Bank Japan2023-12-13 更新40

A novel Imatinib analog inhibitor of chronic myeloid leukemia: design, synthesis, and characterization. Explanation of its folded conformation

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结构生物学

Chronic Myeloid Leukemia (CML) is primarily treated using Imatinib mesylate, a tyrosine kinase inhibitor (TKI) targeting the Bcr-Abl oncoprotein. However, the development of drug resistance and advers

DataONE2025-01-16 更新40

Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic cephalosporin

蛋白质结构

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Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic cephalosporin Descriptor: (2R)-2-[(R)-{[(6S)-6-amino-6-carboxyhexanoyl]amino}(carboxy)methyl]-5-methyl-3,6-d

Protein Data Bank Japan2024-10-30 更新50

Data for: Structure based drug design of Pim-1 kinase followed by pharmacophore guided synthesis of Quinolone-based inhibitors

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化学分析

NMR data for compounds in supplementary material

Mendeley Data2024-06-25 更新40