Animal welfare in experimental orthopedic surgery of dogs: an analysis of the Brazilian view

ABSTRACT: The aim of this paper was to conduct a bibliometry search about Brazilian scientific publications that describe experimental orthopedic surgeries in dogs. It was analyzed 14 publications, and there was wide variation in the number of experimental animals, showing that there is no consensus on the appropriate number for science experiment with dogs. Most articles had been reviewed by an ethics committee (13/14, 92.85%) and only two articles (2/14; 14.28%) did not report the use of analgesic protocol. Among analgesics, morphine was the most widely used, noted in seven studies (7/14; 42.85%). In six of the articles (6/14; 42.85%), the final destination of animals was not informed, but in four experiments (4/14; 28.57%) the dogs were euthanized. In four studies (4/14; 28.57%) the animals were sent for adoption. In conclusion, the ethics in animal research in Brazil has advanced, but is necessary proper planning in sample size.摘要：本研究旨在针对描述犬类实验骨科手术的巴西科研文献开展文献计量学（bibliometry）分析。本次研究共纳入14篇相关文献进行分析，实验动物的数量存在较大差异，表明犬类科学实验的适宜样本量尚未形成统一共识。多数文章已通过伦理委员会审查（13/14，92.85%），仅2篇（2/14，14.28%）未提及镇痛方案的使用情况。在所使用的镇痛药物中，吗啡为最常用药物，共在7项研究中被提及（7/14，42.85%）。6篇文献（6/14，42.85%）未披露实验动物的最终去向，但另有4项实验（4/14，28.57%）的犬只被实施安乐死；4项研究（4/14，28.57%）的实验动物被送往领养机构。综上，巴西的动物研究伦理规范已有所进步，但仍需对样本量进行合理规划。