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Ovarian cancer cell fate regulation by the dynamics between saturated and unsaturated fatty acids

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NIAID Data Ecosystem2026-03-14 收录
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The goal of this study was to determine how the balance between SFAs and UFAs tightly controlled by SCD, regulates OC cell survival and tumorigenicity. Overall design: 1) SCD was stably knocked down by shRNA in OVCAR-5 cells and cultured in low serum condition for 48 hours. Global effects on the transcriptome were examined by RNA-sequencing between shSCD vs shCtrl (in biological triplicates).

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2022-11-11
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