Cannabidiol modulates type I IFN response genes and HIV infection in macrophages. Cannabidiol modulates type I IFN response genes and HIV infection in macrophages

To understand the differential expression of CBD on monocytic cells and the mechanisms by which CBD interacts with our immune system and immune cell signaling. Overall design: To examine the global effects of Cannabidiol (CBD) on transcriptome, we treated THP-1 (monocytic cell line) with either vehicle, CBD alone, 2'3cGAMP alone or CBD and 2'3'cGAMP for 8hrs.