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Genome wide mapping of gH2AX in quiescent and irradiation-induced senescent human fibroblasts

NIAID Data Ecosystem2026-03-11 收录

DNA损伤修复

细胞衰老

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE35884 数据链接链接失效反馈

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资源简介：

We observe preferential accumulation of gH2AX at chromosome ends upon irradiation comparison of quiescent vs senescent human fibroblasts

应用场景：

创建时间：

2019-05-15

DNA损伤修复

蛋白质结构解析

Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain Descriptor: DNA repair and telomere maintenance protein nbs1, GLYCEROL Authors: Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.

Protein Data Bank Japan2023-11-01 更新60

Set 1_S2_molecule_chkpt

肾脏疾病

细胞衰老

Renal artery stenosis (RAS) engenders stenotic-kidney ischemia, dysfunction, and injury, but whether these are mediated by cellular senescence has not been elucidated. Using INK-ATTAC transgenic mice,

DataCite Commons2020-09-24 更新40

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated CMP

DNA损伤修复

酶结构解析

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated CMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHAN

Protein Data Bank Japan2023-10-11 更新20

Additional file 3: Dataset 1. of Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability

表观遗传学

细胞衰老

Ranked list of the 500 genes containing the greatest H4K20me3 enrichment in RS cells. Dataset 2. Ranked list of the 500 genes containing the greatest H4K20me3 enrichment in OIS cells. (XLS 109 kb)

DataCite Commons2024-12-16 更新60

Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate and methylated trinucleotide T-meC-T

DNA损伤修复

蛋白质晶体学

Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate and methylated trinucleotide T-meC-T Descriptor: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB, DNA (5'-D(P*TP*(ME

Protein Data Bank Japan2024-02-21 更新20

Genome wide mapping of gH2AX in quiescent and irradiation-induced senescent human fibroblasts

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