Background. Clinically approved antidepressants modulate the brain’s emotional valence circuits, suggesting that the response of these circuits could serve as a biomarker for screening candidate antid
Voxel-based analyses at p100 voxels). Labels were obtained using the aal toolbox [32]. Broadmann areas were obtained using MRICron (Rorden and Brett, 2000). KE indicate the number of voxels included i
The values represent means + SEM (ng/mg tissue) per group saline-pretreated and saline-challenged (SS) (n = 4); saline-pretreated and METH-challenged (SM) (n = 8); METH-pretreated and saline-challenge
The role of dopamine in cocaine misuse has been extensively documented for the mesocorticolimbic circuit. Preclinical work from earlier lesion studies to recent multidisciplinary investigations has su
Table shows, cluster size, T value of the comparison, significance (p) and location of coordinates (in mm) on Montreal Neurological Institute (MNI) coordinates (x,y,z). L = left, R = right.