MOBSTER empirical estimates.

MOBSTER estimates in 78 PCAWG samples. MOBSTER was run with both ICL and reICL model selection. Default settings were used as outlined in MOBSTER package. VAFs were filtered above 5% VAF and below 70% VAF before application of MOBSTER. Only diploid regions were used. The number of subclones were determined as follows. Any sample contained in the set ({tail = TRUE, c1freq > 0, c2freq > 0}, {tail = FALSE, c1freq & c2freq & c3freq > 0}) were labeled 1 subclone, {tail = TRUE, c1freq & c2freq & c3freq > 0} were labeled as 2 subclones. The remaining samples were labeled 0 subclones. (XLSX)