<b>A relaxation-diffusion MRI dataset of aging mouse brains at 9.4 Tesla</b>

<b>Introduction:</b>This dataset contains relaxation-diffusion MRI (rdMRI) data of mouse brains, aimed at investigating age-related microstructural changes. It includes data collected from five different age groups (2, 6, 12, 18 and 24 months old, six per age group) of mice, acquired with five echo times (22, 37, 52, 67 and 82 ms) at 9.4T Bruker MRI and preprocessed using a specialized pipeline. All animal experiments were conducted in accordance with the Institutional Animal Care and Use Committee of Southern Medical University.<b>Contact infomation:</b>Name: Xinyuan ZhangEmail: [e-mail]<b>Primary acquisition parameters：</b><b>·</b>T2-weighted images- Sequence: 2D TurboRARE- TR/TE = 3200/11 ms- Resolution = 0.08 × 0.08 mm²<br><b>·</b>Diffusion-weighted images- Sequence = 2D multi shot DWI SE-EPI- TR = 3200 ms- TEs = 22, 37, 52, 67 and 82 ms- b-value = 500, 1000, 1500, and 2500 s/mm²- directions = 30, 30, 30, 30- b0 images = 6- Resolution = 0.1 × 0.1 mm²<b>Directory Structure:</b>Due to the upload limitations of FigShare, the DICOM formatted raw data has not been uploaded; only the NIfTI formatted raw data is available. If you require the DICOM format, please feel free to contact us.<br>All subjects the following data were acquired: 1. T2-weighted anatomical data ("anat" folder) 2. Multi-TE diffusion MRI data (acq = Inferior-Superior, "dwi" folder) -ses-01: TE = 22 ms -ses-02: TE = 37 ms -ses-03: TE = 52 ms -ses-04: TE = 67 ms -ses-05: TE = 82 ms 3. Reversed phase encoding multi-TE diffusion MRI data (acq = Superior-Inferior, "reversed phase-encode dwi" folder) -ses-01: TE = 22 ms -ses-02: TE = 37 ms -ses-03: TE = 52 ms -ses-04: TE = 67 ms -ses-05: TE = 82 ms<b>Code and scripts:</b>The REDIM method code can be found in the “code” folder. The processing scripts are organized in the “scripts” folder”