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RNAi library screen for loss of telomeric silencing in T. brucei. Loss of silencing in T. brucei

NIAID Data Ecosystem2026-03-08 收录

基因沉默

RNA干扰

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJEB8746 数据链接链接失效反馈

官方服务：

资源简介：

We performed a genome scale RNAi library screen for loss of telomeric silencing in T. brucei.

应用场景：

创建时间：

2015-03-13

RNA设计

RNA干扰

The evolution of RNA interference (RNAi) and the development of technologies exploiting its biology have enabled scientists to rapidly examine the consequences of depleting a particular gene product i

DataCite Commons2020-09-05 更新220

LM2_ONTARGETPlus_GEFGAP Screen (Data Record 2) .xlsx

Rho GTPase信号通路

RNA干扰

Raw data for the ONTARGETPlus RhoGEF and RhoGAP RNAi screen on LM2 cells

Figshare2017-02-24 更新70

Sequence determinants of dsRNA processing by DICER [Rescue Experiment]

RNA加工机制

RNA干扰

RNA silencing relies on specific and efficient processing of dsRNA by DICER which produces microRNAs (miRNAs) and small interfering RNAs (siRNAs). However, our current knowledge of DICER's specificity

NIAID Data Ecosystem60

PRC1.6 and SETDB1-mediated repression of germline genes in the early embryo precedes DNA methylation-mediated silencing.. PRC1.6 and SETDB1-mediated repression of germline genes in the early embryo precedes DNA methylation-mediated silencing.

胚胎发育表观遗传

基因沉默

Silencing of a subset of germline genes is dependent upon DNA methylation (DNAme) post-implantation. However, these genes are generally hypomethylated in the ICM, implicating alternative silencing pat

NIAID Data Ecosystem110

Sup Table.1

RNA干扰

miRNA序列

The sequences of siRNAs for RNA interference.

NIAID Data Ecosystem70