Adenovirus composition, proteolysis, and disassembly studied by in-depth qualitative and quantitative proteomics.

Data from ProteomeXchange, PXD ID: PXD000591. File: HAdV_LysN_OrbiXL.msf. Published as part of J Biol Chem. 2014 Apr 18;289(16):11421-30 . From the Abstract: {{i}} Using high-resolution MS-based proteomics in combination with multiple protease digestion, we profiled, with on average 90% sequence coverage, all 13 viral proteins present in an human adenovirus (HAdV) vector. This in-depth profile provided multiple peptide-based evidence on intrinsic protease activity affecting several HAdV proteins. {{/i}}