half_life_obach

## Dataset Details ### Dataset Description Half life of a drug is the duration for the concentration of the drug in the body to be reduced by half. It measures the duration of actions of a drug. This dataset deposited version under CHEMBL assay 1614674. - **Curated by:** - **License:** CC BY 4.0 ### Dataset Sources - [corresponding publication](https://doi.org/10.1124/dmd.108.020479) - [data source](https://tdcommons.ai/single_pred_tasks/adme/#half-life-obach-et-al) ## Citation **BibTeX:** ```bibtex @article{Obach2008, doi = {10.1124/dmd.108.020479}, url = {https://doi.org/10.1124/dmd.108.020479}, year = {2008}, month = apr, publisher = {American Society for Pharmacology and Experimental Therapeutics (ASPET)}, volume = {36}, number = {7}, pages = {1385--1405}, author = {R. Scott Obach and Franco Lombardo and Nigel J. Waters}, title = {Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds}, journal = {Drug Metabolism and Disposition} ```## 数据集详情 ### 数据集描述 药物半衰期（half life）指药物在体内浓度降低至初始浓度一半所需的时长，可用于表征药物在体内的作用持续时长。本数据集的存档版本隶属于CHEMBL测定编号1614674。 - **数据整理者：** - **授权协议：** CC BY 4.0 ### 数据集来源 - [相关研究文献](https://doi.org/10.1124/dmd.108.020479) - [数据来源](https://tdcommons.ai/single_pred_tasks/adme/#half-life-obach-et-al) ## 引用信息 **BibTeX格式引用：** bibtex @article{Obach2008, doi = {10.1124/dmd.108.020479}, url = {https://doi.org/10.1124/dmd.108.020479}, year = {2008}, month = {四月}, publisher = {美国药理与实验治疗学会（ASPET)}, volume = {36}, number = {7}, pages = {1385--1405}, author = {R·斯科特·奥巴奇、佛朗哥·隆巴尔多、奈杰尔·J·沃特斯}, title = {670种药物化合物人体静脉给药药代动力学参数数据库的趋势分析}, journal = {《药物代谢与处置》（Drug Metabolism and Disposition)} }