SynSysNet is based on an expert-curated list of 1.000 human genes, specific to the synapse, information on resulting proteins, their 3D structure, binding small molecules Protein-Protein-Interactions
In recent years, the rapid increase in the production and environmental release of synthetic organic chemicals has raised serious concerns about their potential adverse effects on human health and the
Comparing biological similarity with in vitro test is expected to improve the reliability of read-across for systemic toxicity without animal test. However, because of few case studies, it was hindere