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piRNA 3' end formation and phasing in Aedes aegypti

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NIAID Data Ecosystem2026-03-11 收录
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In this study, we provide new insights into the biogenesis mechanisms that govern piRNA 3' end generation and maturation in Aedes mosquitoes. Additionally, we provide data showing that endogenous piRNAs are able to target newly infecting viruses. Moreover, piRNA production is expanded beyond the site of initial targeting, indicating the piRNA pathway may be able to adapt to novel viruses.

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2020-07-15
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