Overlap between TS-DMSs and active enhancers (H3K27ac and H3K4me1 marks).
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1) Number of TS-DMSs within enhancers with H3K27ac marks. 2) Number of surveyed CpGs within enhancers with H3K27ac marks. 3) The quotient of two ratios, (number of TS-DMS within H3K27ac enhancers/total number of TS-DMS) and (total number of surveyed CpGs within H3K27enhancers/total number of surveyed CpGs in the genome). 4) p-value calculated according to the distribution of the fold enrichments generated from simulation of 100,000 iterations. 5) While these enhancers are derived from cortex the TS-DMS are derived from whole brain.
创建时间:
2013-09-12



