Supplementary Table S5 from Extracellular ATP and CD39 Activate cAMP-Mediated Mitochondrial Stress Response to Promote Cytarabine Resistance in Acute Myeloid Leukemia
WEE1 is a cell cycle and DNA damage response kinase that is emerging as a therapeutic target for cancer. AZD1775 is a small molecule inhibitor of WEE1, currently in early phase clinical trials as a si
A project to explore the acquisition of drug resistance mechanisms in a K562 erythroblastic leukemia cell line, with induced resistance to the tyrosine kinase inhibitor, dasatinib. Cells were exposed
Generated AZA resistant cell line (TAR) and analysis markedly different gene expression levels between THP-1 and TAR. Overall design: Two condition experiment, THP-1 control vs. AZA resistant cell lin
For RNAseq, mRNA was extracted from spleen and bone marrow of venetoclax resistant and matched parental PDX leukemia cells using RNeasy kit (Qiagen). Non-stranded RNA-seq libraries were generated usin
