Direct comparison of results for the same outcomes in the current and previous studies.

Outcomes were either ΔDAS28 at 3 or 6 months, or the EULAR criteria, which were used as a comparison of non-responders (NR) with responders (good + moderate responders (GR + M)) at 3 months, or a comparison of NR with GR either at 3 or 6 months. Only previous studies with significant associations are included. Comparison of effect size and direction, and of p values.