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EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq]

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NIAID Data Ecosystem2026-03-13 收录
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We reported here the gene expression profiles that were mediated upon the treatment of EZH2 inhibitor in two hormone-refractory prostate cancer cell lines: the sensitive, AR-positive abl cells and the insensitive, AR-null DU145 cells. Overall design: We treated both types of prostate cancer cells with two different EZH2 inhibitors (GSK126 or EPZ-6438) at final concentrations of 5 uM for 60-72 hrs, and then collected RNAs for gene expression profiling.

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2022-02-09
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