This dataset contains the results of Avana library CRISPR-Cas9 genome-scale knockout (prefixed with Achilles) as well as mutation, copy number and gene expression data (prefixed with CCLE) for cancer
Image data related to Nishimasu, Yamano et al., Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Mol Cell (2017) http://dx.doi.org/10.1016/j.molcel.2017.04.019
For a long time, scientists have been trying to manipulate genes. Recently, University of Pittsburgh in USA Alexander Deiters finds a way to control this process with higher accuracy . Light is what h
To identify essential gene responding to anti-PD-1 immunotherapy, we performed in vivo Genome-scale CRISPR-Cas9 knockout screening. We found that cohesin complex invovled in regulation of anti-PD-1 im
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii Descriptor: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... Authors: Jiang, F, Ma, E, Lin, S, Doudna, J.A. D