Pharmacokinetic parameters for belinostat after 30 min i.v. infusion in Phase I trial.
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Abbreviation: Cmax, maximum concentration; Tmax, time to maximum concentration; AUC0–24 h, area under the curve from 0 to 24 h; T1/2, half-life at the elimination phase; CL, clearance; Vz, volume of distribution. *Mean ± SD; AUC ratio was calculated based on AUC0–24 h of Bel-G (belinostat-G) over AUC0–24 h of Bel (belinostat).
创建时间:
2015-12-02



