Illuminating Biological Enigmas with Advanced Fluorescent Tools

Advanced fluorescence imaging techniques have revolutionized our understanding of biological systems in the last few decades. Be it the examination of tiny cellular organelles or protein biomarkers of disorders such as dementia, these techniques have offered unique insights by enabling enquiries into their nanometer-size dimensions and dynamic, highly versatile environments. However, we still lack the tools to utilize the massive potential of these advanced imaging techniques to the fullest. This work is aimed at bridging this gap, by generating advanced fluorescent probes and sensors compatible with these techniques, illuminating the biological enigmas that have plagued us for centuries.