This was a pilot study to evaluate the gut microbial signature in PAH. This is data from 28 pairs of patients (PAH and non-PAH control) who underwent shotgun metagenomics microbiome sequencing. We ide
To explore the role played by senescent cells in mice models of pulmonary hypertension we exposed young C57BL6/j mice to 8 days hypoxia or normoxia and treated with senolytic drug ABT-263 (50mg/kg/day
HPASM were cultured for 48 hours in 96 well plates with media alone or with iE-DAP (0.01–10 µg/ml), C12-iE-DAP (0.001–1 µg/ml) and LPS (0.001–1 µg/ml). Results are expressed as mean ± SEM for n = 4 fr
