The data are presented as median and interquartile range or as number (%). IGRA, interferon gamma release assay; QFT-GIT, QuantiFERON-TB Gold In-Tube; +, positive; -, negative; I, indeterminate. aP va
*LOA, bias, SDD, and W-S SD are in IU/mL of IFN-γ. †Directionality for bias and LOA comparisons: Lab1-Lab2, Lab1-Lab3, Lab2-Lab3. §Includes 7 subjects with discordant QFT-GIT interpretations. #Concord
The prompt diagnosis of active tuberculosis (ATB) is still a challenge in clinical practice, especially in TB-endemic countries. We prospectively enrolled consecutive patients with suspected pulmonary
Neutrophils have been recognized to play an important role in the pathogenesis of tuberculosis in recent years. Interferon-induced blood transcriptional signatures in ATB are predominantly driven by n