Datafiles associated with Network of hotspot interactions cluster tau amyloid folds. The alascan files contain the averaged and raw outputs of the in silico alanine scan conducted on tau fibrils
Arc repressor mutants containing from three to 15 multiple-alanine substitutions have spectral properties expected for native Arc proteins, form heterodimers with wild-type Arc, denature cooperatively
MreB is a protein involved in cell shape. We made a mutant library to determine important residues. Some mutants completely lost cell shape and were sequenced for possible suppressor mutations.
While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccination strategies, there is mounting evidence to suggest that antibodies with Fc effector function also contr
