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CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy. CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy

NIAID Data Ecosystem2026-03-11 收录

基因编辑治疗

疾病模型研究

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA606799 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2020-02-14

神经学分析

疾病模型研究

Differences in DTI parameters of WT-SOD1 mice between 10 and 17 weeks of age.

NIAID Data Ecosystem40

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice. Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

基因编辑治疗

肥厚型心肌病

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

QMAR (Quality of Movement Assessment for Rehabilitation)

康复治疗评估

疾病模型研究

使用 6 个 Primesense 相机（3 个不同的正面视图和 3 个不同的侧面视图）记录 QMAR，其中有 38 名健康受试者，8 名女性和 30 名男性。受试者由物理治疗师训练，在模拟三种疾病的同时进行两种不同类型的运动，从而产生五种总体可能性：在模拟帕金森 (W-P)、中风 (W-S) 和跛行 (W-L) 时返回到大致原始位置，与帕金森 (SS-P) 和中风 (SS-S) 一起站立和坐下。

OpenXLab10

Modelling, Optimization and Comparable Efficacy of T cells and HSC Gene Editing for treating HIGM1

基因编辑治疗

免疫细胞疗法

Precise correction of the CD40LG gene in T cells and hematopoietic stem/progenitor cells (HSPC) holds promise for treating X-linked hyper-IgM Syndrome (HIGM1), but its actual therapeutic potential rem

NIAID Data Ecosystem20

Precise correction of heterozygous SHOX2 mutations in hiPSCs derived from patients with atrial fibrillation via genome editing and sib-selection

基因编辑治疗

心房颤动模型

Patient-specific human induced pluripotent stem cells (hiPSCs) offer unprecedented opportunities for the investigation of multigenic disease, personalized medicine, and stem cell therapy. For heteroge

NIAID Data Ecosystem20

CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy. CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy

资源简介：

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