相关数据集
SWI/SNF complex mutations promote thyroid tumor progression and resistance to redifferentiation therapy (ATAC-seq, Fig2)
Recurrent mutations in genes encoding subunits of the SWI/SNF chromatin remodeling complex occur commonly in human cancers of different lineages, including advanced thyroid cancers. Thyroid-specific l
NIAID Data Ecosystem40
MED16 negatively regulates erythropoiesis and myelopoiesis through modulation of chromatin accessibility. MED16 negatively regulates erythropoiesis and myelopoiesis through modulation of chromatin accessibility
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
NIAID Data Ecosystem00
Genome-wide binding profile of Smad3 and Smad7 in mouse Ch12 cell line (RNA-Seq)
Mammalian genome encodes approximately 1,700 transcription factors (TFs), 1,300 out of which have sequence specific binding motifs. Transcription in mammalian cells is regulated by the recruitment of
NIAID Data Ecosystem00
Assay for transposase-accessible chromatin-sequencing (ATAC-seq) of liver samples in Wtapflox/flox and hepatocyte-specific Wtap knockout (Wtap-HKO) mice
Purpose: The goal of this study is to determine whether hepatic deletion of Wtapaffects chromatin accessibility. Methods: Each liver sample was pooled from three Wtap-HKO and Wtapflox/flox mice, respe
NIAID Data Ecosystem00
Chromatin accessibility analysis of human mesenchymal stem cells. Chromatin accessibility analysis of human mesenchymal stem cells
We integrated ATAC-seq analyses of human MSC with CRISPRi screening to identify potential regulatory regions controlling UBE2E2 expression and/or UBE2E1 expression. Overall design: Duplicate human MSC
NIAID Data Ecosystem00
