Multiple system atrophy (MSA) is a rare adult-onset neurodegenerative disease of unknown cause, with no effective therapeutic options, and no cure. Limited work to date has attempted to characterize t
FUS/TLS is an RNA/DNA-binding protein associated with neurodegenerative diseases including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Previously, we found that a prion-like d
Exclusion and inclusion criteria used for recruiting normal controls (NC) and subjects with Alzheimer’s disease (AD) and Parkinson’s disease in this study.
Raw data to the paper "Lifetime risk of Neurodegeneration with brain iron accumulation (NBIA) disorders calculated from genetic databases". All pathogenic variants, their allele frequencies as listed
Introduction Cerebral amyloid angiopathy (CAA) is a vasculopathy characterized by amyloid-beta (Aβ) deposition in the walls of the leptomeningeal and cortical blood vessels. In a minority of patients