Live offspring at weaning from Chd3fl/+ X Chd3fl/+;Tie2-Cre+ crossesa.

Figshare2020-07-13 更新2026-04-28 收录

数据链接：

https://figshare.com/articles/dataset/Live_offspring_at_weaning_from_i_Chd3_i_sup_i_fl_i_sup_X_i_Chd3_i_sup_i_fl_i_sup_i_Tie2-Cre_i_sup_i_i_sup_crosses_sup_a_sup_/12647540 数据链接链接失效反馈

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资源简介：

Live offspring at weaning from Chd3fl/+ X Chd3fl/+;Tie2-Cre+ crossesa.

创建时间：

2020-07-13

Cdk5 条件敲除小鼠（Floxed-cdk5）

发育基因调控

条件性基因敲除

Cdk5对中枢神经系统的正常发育至关重要，并参与成年神经系统的突触传递、突触可塑性和神经元信号传导等功能。将Cdk5-loxP小鼠与Cre转基因小鼠杂交，其中Cre的表达由Nefh启动子驱动，从而在胚胎第16.5天左右开始产生在特定神经元中限制性缺失Cdk5基因的活的Cdk5条件性敲除小鼠。在携带杂合Cre等位基因的Cdk5条件敲除小鼠中，有25%的小鼠存在神经元迁移缺陷，这些缺陷局限于神经元迁移

中国科技资源共享网2026-07-08 更新30

Fig4_Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype

心血管发育遗传学

胚胎心脏MRI分析

AmiraMesh File from Magentic Resonance Imaging data of embryo 302.4 (Pax9 deleted from the second heart field, E15.5 embryo). Shown in panels D, E, F & H in Figure 4 of the paper "Msx1 haploinsuffici

NIAID Data Ecosystem30

Dual leucine zipper kinase is required for excitotoxicity induced neuronal degeneration. Mus musculus

神经退行性机制

条件性基因敲除

To investigate the role of DLK in the adult brain, we generated mice in which excision of the DLK allele can be temporally controlled to avoid the lethality observed at early postnatal ages in DLK nul

NIAID Data Ecosystem10

Comprehensive proteomic and transcriptomic characterization of hepatic expression signatures affected in p14 liver conditional knockout mice

肝脏分子信号传导

条件性基因敲除

Scaffold proteins regulate intracellular MAP kinase signaling by providing critical spatial and temporal specificity. We have shown previously that the scaffold protein MEK1 partner (MP1) is localized

NIAID Data Ecosystem30

Expression of the SNARE Protein SNAP-23 Is Essential for Cell Survival

SNARE蛋白

条件性基因敲除

Members of the SNARE-family of proteins are known to be key regulators of the membrane-membrane fusion events required for intracellular membrane traffic. The ubiquitously expressed SNARE protein SNAP

NIAID Data Ecosystem10

Live offspring at weaning from Chd3fl/+ X Chd3fl/+;Tie2-Cre+ crossesa.

资源简介：

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