Bile acids and risk of adverse cardiovascular events and all-cause mortality in patients with acute coronary syndrome

To examine associations of primary and secondary BAs with risk of cardiovascular events and all-cause mortality in ACS. A panel of 10 BAs consisting of primary and secondary BAs, was significantly associated with increased risk of MACE. Furthermore, 4 BAs were associated with all-cause mortality.本研究旨在探究急性冠脉综合征（Acute Coronary Syndrome, ACS）患者体内原发性与继发性胆汁酸（Bile Acids, BAs）与心血管事件及全因死亡率的关联。研究结果显示，由10种原发性及继发性胆汁酸组成的胆汁酸谱与主要不良心血管事件（Major Adverse Cardiovascular Events, MACE）风险升高显著相关。此外，另有4种胆汁酸与全因死亡率存在关联。