active PL: samples containing active CPD-photolyase, inactive PL: samples containing inactive CPD-photolyase.Summarized fold change values by microarray results of the selected 9 CPD-dependent genes.
RNA-DNA hybrids are naturally occurring obstacles that must be overcome by the DNA replication machinery. In the absence of RNase H enzymes, RNA-DNA hybrids accumulate, resulting in replication stress
Double-strand breaks (DSBs) are critical lesions in genomic DNA, and their accurate repair is essential for maintaining genome stability. The nuclear actin cytoskeleton has been implicated in homology