There is a compelling and growing need to accurately predict the impact of amino acid mutations on protein stability for problems in personalized medicine and other applications. Here the ability of 1
*cTnCT53C: three mutations (C35S, C84S, and T53C) are introduced into native cTnC for IAANS labelling at the T53C position [21].aSignificantly different from their respective WT control values (pbSign
CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c1(c(cnn1C)C(NCc2ccn[nH]2)=O)C(Nc4nc3nc(cn3cc4)c5ccccc5)=O, micromolar IC50=0.0025705 Descriptor: 1-methyl-N~5~-[(4S)-2-phenylimidazo[1,
