RNA-binding proteins are instrumental for post-transcriptional gene regulation, yet transcriptome-wide methods to profile RNA-protein interactions remain technically challenging. We present an improve
The prediction of binding sites (peak-calling) is a common task in the data analysis of methods such as crosslinking immunoprecipitation in combination with high-throughput sequencing (CLIP-Seq). The
Crosslinking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins (RBPs). We developed a method for CLIP data analysis and applied it to