Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
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2024-05-10
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Analysis of High Molecular Weight RNA-induced silencing complex (HMW-RISC) in CD8+ T cells identifies miR-7 as a modulator of T cell activation. Analysis of High Molecular Weight RNA-induced silencing complex (HMW-RISC) in CD8+ T cells identifies miR-7 as a modulator of T cell activation
To identify the miRNAs expected to be potent in suppressing targets, we followed HMW RISC formation upon activation of CD8+ T cells. We show that while most miRNAs distribute between HMW and LMW RISC
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The Transcription Factor ZFfx Regulates Peripheral T Cell Self-renewal and Proliferation
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CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumors.. CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumors.
Here, we report the immune-mediated mechanisms underlying the improved activity of immune checkpoint blockade in glycolysis-defective tumor models. Overall design: Correlate glycolysis-related genes w
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Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy. Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy
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DataSheet_1_Hierarchical and Dynamic Regulation of Defense-Responsive Specialized Metabolism by WRKY and MYB Transcription Factors.pdf
The plant kingdom produces hundreds of thousands of specialized bioactive metabolites, some with pharmaceutical and biotechnological importance. Their biosynthesis and function have been studied for d
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